Faculty Profile

About

I am an enthusiastic, practical person, passionate about teaching and research. I have completed my B.Sc. with Sir C. V. Raman fellowship. After my M.Sc. in Solid State Physics specialization, I have pursued my Ph.D. in X-ray crystallography, on “Structural Investigation of Some Heterocyclic Compounds of Biological Interest”, at the National Single Crystal X-ray Diffractometer Laboratory, University of Mysore. As a research student, I have served to set up an organic/inorganic materials synthesis crystallography lab, published good number of research papers in international and national peer-reviewed journals apart from the publications in conferences and symposia. I have received the IUCr Young Scientist Award for my significant contribution to the field of X-ray crystallography at the 16th conference of the Asian Crystallographic Association, held at the National University of Singapore, in 2019.
My research work includes the synthesis, spectroscopic characterization, crystal growth, X-ray diffraction and computational studies of organic/inorganic materials to explore their characteristics such as physicochemical, optical and biological properties. I am also interested on construction of metal organic frameworks, role of hydrogen bond interactions, synthesis of liquid crystals, nano-crystalline structures and explore their significant applications.
Currently, I am working on the synthesis of novel organic/inorganic heterocyclic compounds and their structure-property correlation.

I do believe strongly in "determination, dedication, and hard work" which are the three important keys to success.

Education

• Ph.D. - Condensed Matter Physics: X-ray Crystallography
  University of Mysore
  Passed Year: 2018 | Program Type: FullTime
• KSET - Physics
  KSET center, University of Mysore
  Passed Year: 2017 | Program Type: FullTime
• M.Sc. in Physics - Solid State Physics
  University of Mysore
  Passed Year: 2014 | Program Type: FullTime
• B.Sc. - Physics, Chemistry and Mathematics
  University of Mysore
  Passed Year: 2012 | Program Type: FullTime

Selected Publications

• Journal | Published On : 14-07-2024
  Karthik Kumara et. al
  Structural and computational exploration of zwitterionic and quinoidal forms in Schiff base compound
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• Journal | Published On : 14-07-2024
  Karthik Kumara et. al
  Crystal structure, supramolecular features and antibacterial activities of a Cu (II) Schiff base complex using a bidentate N2O2 donor Schiff base ligand
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• Journal | Published On : 05-01-2024
  Karthik Kumara et. al
  Regioselective benzylation of imidazo[1,5-a]pyridines and indoles via iodine catalyzed reaction using alcohols - An approach to crystal structure prediction, DFT studies and Hirshfeld surface analysis
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• Journal | Published On : 01-01-2024
  Karthik Kumara et. al
  Hydrothermal synthesis of Bi2S3 nanoparticle as a prospective electrode for supercapacitor
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• Journal | Published On : 15-12-2023
  Karthik Kumara et. al
  Microwave-Assisted Synthesis and Characterization of Some Aldehyde Derivatives of Imidazo[2,1-b][1,3,4]thiadiazole: Crystal Structure Insights, In-Silico and Biological Studies
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• Journal | Published On : 10-10-2023
  Karthik Kumara et. al
  Jahn-Teller distortion in SP-like [Cu(bipy)(triamine)].2BF4 complexes with novel N-H…F/C-H…F synthon: XRD/HSA-interactions, physicochemical, electrochemical, DFT, docking and COX/LOX inhibition
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• Journal | Published On : 10-05-2023
  Karthik Kumara et. al
  Synthesis, characterization, E/Z-isomerization, DFT, optical and 1BNA docking of new Schiff base derived from naphthalene-2-sulfonohydrazide
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• Journal | Published On : 24-02-2023
  Karthik Kumara et. al
  Sulfur Nanoparticle as an Effective HEK-293 Anticancer Agent
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• Journal | Published On : 01-02-2023
  Karthik Kumara et. al
  "Structural elucidation of 1:4:4 stochiometric form of thymine – gallic acid cocrystal hydrate: Hirshfeld surface analysis, 3D energy framework, DFT calculations, and SARS CoV-2 docking studies", Journal of Molecular Structure, 135072, 2023.
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• Journal | Published On : 29-11-2022
  Karthik Kumara et. al
  "One-pot reproducible Sonosynthesis of trans-[Br(N?N’)Cu(?Br)2Cu(N?N’)Br] dimer:[H….Br S(9)] synthons, spectral, DFT/XRD/HSA, thermal, docking and novel LOX/COX enzyme inhibition", Journal of Molecular Structure, 134626, 2022.
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• Journal | Published On : 22-10-2022
  Karthik Kumara et. al
  "2,6-Disubstituted Imidazothiadiazole 5-Carbaldehyde: Synthesis, Crystal Structure Elucidation and in-silico Studies", Chemical Data Collections, 100962, 2022.
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• Journal | Published On : 28-09-2022
  Karthik Kumara et. al
  "Structural investigations and theoretical insights of a polymethoxy chalcone derivative: Synthesis, crystal structure, 3D energy frameworks and SARS CoV-2 docking studies", Journal of Molecular Structure, 134226, 2022.
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• Journal | Published On : 07-09-2022
  Karthik Kumara et. al
  "Influence of Counter Ions on Supramolecular Structures of Copper(II) Complexes Derived from 1,8-Naphthalimide Tecton", Journal of Molecular Structure, 134086, 2022.
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• Journal | Published On : 10-08-2022
  Karthik Kumara et. al
  "Copper(i) complexes with quinolone appended 1,8-naphthalimide conjugates: structural characterization, DNA and protein binding and cytotoxicity studies", New Journal of Chemistry, 2022.
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• Journal | Published On : 20-06-2022
  Karthik Kumara et. al
  "Gallic acid-butyramide monohydrate cocrystal: Crystal growth, Structural insights, Theoretical calculations and Molecular docking studies against COVID-19 main protease", Current Chemistry Letters, 11, 2022.
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• Journal | Published On : 31-05-2022
  Karthik Kumara et. al
  "Structural-property relationship in halogen-bonded Schiff base derivative: Crystal structure, computational and SARS-CoV-2 docking studies", Journal of Molecular Structure, 1265, 133409, 2022. https://doi.org/10.1016/j.molstruc.2022.133409
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• Journal | Published On : 06-02-2022
  Karthik Kumara et. al
  "Syntheses, structural characterization and evaluation of the anti-tubercular activity of copper (II) complexes containing 3-methoxysalicylaldehyde-4-methylthiosemicarbazone", Journal of Molecular Structure, 1257, 132589, 2022. https://doi.org/10.1016/j.molstruc.2022.132589
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• Journal | Published On : 01-12-2021
  Karthik Kumara et. al
  “Fluorophore Tagged Mixed Ligand Copper (II) Complexes: Synthesis, Structural Characterization, Protein Binding, DNA Cleavage and Anticancer Activity”, Chemistry Select, 6(45), 12666-12676, 2021. https://doi.org/10.1002/slct.202103314
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• Journal | Published On : 25-11-2021
  Karthik Kumara et. al
  “Design, synthesis of coumarin tethered 1, 2, 3-triazoles analogues, evaluation of their antimicrobial and ?-amylase inhibition activities” Journal of Chemical Sciences, 133 (4), 1-8, 2021. https://doi.org/10.1007/s12039-021-01997-0
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• Journal | Published On : 15-07-2021
  Karthik Kumara et. al
  “Design, synthesis, characterization, and antioxidant activity studies of novel thienyl-pyrazoles”, Heliyon, 7(7), e07592, 2021. https://doi.org/10.1016/j.heliyon.2021.e07592
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• Journal | Published On : 25-06-2021
  Karthik Kumara et. al
  “Square Planar trans?N2O2 Cu(II) Complex: Synthesis, Crystal Structure, Hirshfeld Surface, DFT, Antimicrobial and Docking Studies”, ChemistrySelect, 6 (24), 6240-6255, 2021. https://doi.org/10.1002/slct.202101149
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• Journal | Published On : 05-05-2021
  Karthik Kumara et. al
  “8-Hydroxyquinoline derived p-halo N4-phenyl substituted thiosemicarbazones: Crystal structures, spectral characterization and in vitro cytotoxic studies of their Co(III), Ni(II) and Cu(II) complexes”, Bioorganic Chemistry, 112, 104962, 2021. https://doi.org/10.1016/j.bioorg.2021.104962
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• Journal | Published On : 16-12-2020
  Karthik Kumara et. al
  “Exo-Endo Isomerism, MEP/DFT, XRD/HSA-Interactions of 2, 5-Dimethoxybenzaldehyde: Thermal, 1BNA-Docking, Optical, and TD-DFT Studies”, Molecules, 25 (24), 5970, 2020. https://doi.org/10.3390/molecules25245970
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• Journal | Published On : 26-08-2020
  Karthik Kumara et. al
  “Environmentally benign synthesis of substituted pyrazoles as potent antioxidant agents, characterization and docking studies”, Journal of the Iranian Chemical Society, 18(2), 479-493, 2021. https://doi.org/10.1007/s13738-020-02042-6
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• Journal | Published On : 13-06-2019
  Karthik Kumara et. al
  “Design, structural, C–H…. H–C supramolecular interactions and computational investigations of Cd (N? N ?) X2 complexes based on an asymmetrical 1, 2-diamine ligand: physicochemical and thermal analysis”, Journal of Coordination Chemistry, 1-13, 2019. https://doi.org/10.48317/IMIST.PRSM/morjchem-v7i2.16070
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• Journal | Published On : 21-09-2018
  Karthik Kumara et. al
  “Synthesis and structural studies of 1-phenyl-1, 3-butanedione copper (II) complexes as an excellent antimicrobial agent against methicillin-resistant Staphylococcus aureus”, Inorganica Chimica Acta, 484, 227-236, 2019. https://doi.org/10.1016/j.ica.2018.09.049
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• Journal | Published On : 19-06-2018
  Karthik Kumara et. al
  “Design and Amberlyst-15 mediated synthesis of novel thienyl-pyrazole carboxamides that potently inhibit Phospholipase A2 by binding to an allosteric site on the enzyme”, Bioorganic Chemistry, 80, 444-452, 2018. https://doi.org/10.1016/j.bioorg.2018.06.023
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• Journal | Published On : 14-06-2018
  Karthik Kumara et. al
  “Amberlyst-15 catalyzed synthesis of novel thiophene–pyrazoline derivatives: spectral and crystallographic characterization and anti-inflammatory and antimicrobial evaluation”, Research on Chemical Intermediates, 44(11), 6453-6468, 2018. https://doi.org/10.1007/s11164-018-3501-2
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• Journal | Published On : 05-06-2018
  Karthik Kumara et. al
  “Synthesis, spectral characterization and X-ray crystal structure studies of 3-(benzo[d][1,3]dioxol-5-yl)-5-(3-methylthiophen-2-yl)-4,5-dihydro-1H-pyrazole-1-carboxamide: Hirshfeld surface, DFT and thermal analysis”, Journal of Molecular Structure, 1161, 285-298, 2018. https://doi.org/10.1016/j.molstruc.2018.02.068
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• Journal | Published On : 31-01-2018
  Karthik Kumara et. al
  “Crystal Structure Studies and Hirshfeld Surface Analysis of 5-(4-methoxyphenyl)-3-(thiophen-2-yl)-4,5-dihydro-1H-pyrazole-1-carbothioamide”, Chemical Data Collections, 13-14, 40-59, 2018. https://doi.org/10.1016/j.cdc.2018.01.001
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• Journal | Published On : 04-12-2017
  Karthik Kumara et. al
  “Crystal structure of SAM-dependent methyltransferase from Pyrococcus horikoshii”, Acta Crystallographica Section F: Structural Biology Communications, F73, 706-712, 2017. https://doi.org/10.1107/S2053230X17016648
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Other Information

Academic Excellences:
• The Sir C.V. Raman fellowship during B.Sc. by government of Karnataka.
• The Student Travel Grant - 2017 by IUCr at the 24th international conference, India.
• The International Travel Grant by DST-SERB (Grant no. ITS/2019/005798).
• The IUCr Young Scientist Award for the year 2019, at AsCA-2019 by the National University of Singapore.

Professional Memberships:
• Member, Indian Science Congress Association, Kolkata
• Member, Indian Crystallographic Association, Bengaluru

Reviewer:
• MDPI - Molecules
• Journal of Molecular Structure
• Materials Research Express
• Crystals
• Agronomy
• Processes
• Sustainability
• Chemical Data Collections
• Heliyon
• Polymers
• Water
• Micromachines
• Journal of Physics and Chemistry of Solids
• Computational and Theoretical Chemistry
• Structural Chemistry
• Symmetry

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